Monday, February 13, 2012

Quorum Sensing

Here's an article I found really interesting about quorum sensing inhibitors.  Quorum sensing in bacteria is a topic I've been interested in for a while now and some people believe it may be the future to antibiotics.  The idea is that bacteria communicate and don't release virulence until they sense that there are enough bacteria present that it will be effective.  The hope is that some day anti quorum sensing molecules can be found or developed in order to work as antibiotics.   Finding inhibitors like the ones mentioned in this article are the key to these types of antibiotics working.

http://www.sciencedirect.com/science/article/pii/S0956713511003616

If you guys want to know more about quorum sensing here is an old article from when it was first discovered.
http://www.annualreviews.org/doi/full/10.1146/annurev.micro.55.1.165

Here's a great TED video of Bonnie Bassler, one of the leading researchers in quorum sensing, talking about her discoveries.
http://www.youtube.com/watch?v=TVfmUfr8VPA

Enjoy!

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