Monday, April 11, 2011

Biomagnification of Toxins in Marine Food Webs

The Interdepartmental Graduate Program in Marine Sciences is sponsoring a special seminar that is of potential interest across a broad span of biology (see Abstract). Dr. Trapido-Rosenthal is visiting UCSB for Friday's Symposium honoring Professor Dan Morse (Hank earned his PhD with Dan in 1985).  We hope you can join us for this seminar.

Special IGP Marine Science Seminar

Thursday, April 14, 2011
12 noon
MSRB Auditorium
(pizza lunch following, on MSRB 2nd floor balcony)

Henry (Hank) Trapido-Rosenthal
Associate Research Scientist
School of Ocean and Earth Science and Technology
University of Hawaii

Biomagnification of Toxins in Marine Food Webs

Some dinoflagellate algae and cyanobacteria produce toxins that have human health endpoints after being biomagnified as they move upwards through marine food webs. We are studying two of these toxins: (a) ciguatoxin, which is produced by dinoflagellates in the genus Gambierdiscus, and which causes poisoning in humans who eat toxin-containing reef fish; and (b) β-methylaminoalanine (BMAA), a “nonprotein” amino acid which can be produced by some cyanobacteria, and which can have neurotoxic effects on organisms at higher trophic levels after food web biomagnification. In this talk, I will first describe the results of our work with ciguatoxin here in the Hawaiian Islands. I will then describe work being done by ourselves and our international colleagues to address some mysteries associated with the ways in which BMAA is biomagnified and exerts its toxic effects.

Bienfang, P.K., DeFelice, S.V., Laws, E.A., Brand, L.E., Bidigare, R.R., Christensen, S., Trapido-Rosenthal, H., Hemscheidt, T.K., McGillicuddy Jr., D.HJ., Anderson, D.M., Solo-Gabriele, H.M., Boehm, A.B., and Backer, L.C. (2011) Prominent human health impacts from several marine microbes: History, ecology, and public health implications. Int. J. Microbiol., ID 152815, 15 pages.
Venn, A.A., Loram, J.E., Trapido-Rosenthal, H.G., Joyce, D.A., and Douglas, A.E. (2008) The importance of time and place: How genetically-different Symbiodinium algae are distributed in a variable coral reef symbiosis. Biol. Bull., 215:243-252.
Loram, J.E., Boonham, N., O’Toole, P., Trapido-Rosenthal, H.G., and Douglas, A.E.  (2007) Molecular quantification of symbiotic dinoflagellate algae Symbiodinium in corals. Biol. Bull., 212:259-268.
Loram, J.E., Trapido-Rosenthal, H.G., and Douglas, A.E. (2007) Functional significance of symbiont clade in a coral reef symbiosis. Molec. Ecol. 16: 4849-4857.
Venn, A.A., Wilson, M.S., Trapido-Rosenthal, H.G., Keely, B.J., and Douglas, A.E. (2006) The impact of coral bleaching on the pigment profile of the symbiotic alga Symbiodinium. Plant, Cell Env. 29:2133-2142.
Yasuhara-Bell, J., Yang, Y., Barlow, R., Trapido-Rosenthal, H., and Lu, Y. (2010) In vitro evaluation of marine microorganism extracts for anti-viral activity. Virol. Jour. 7: 182-193.
Anderson, P.A.V., and Trapido-Rosenthal, H.G. (2009) Physiological and chemical analysis of neurotransmitter candidates at a fast excitatory synapse in the jellyfish Cyanea capillata (Cnidaria, Scyphozoa). Invert. Neurosci. 9:167-173.
Toledo, G., Green, W., Gonzalez, R., Christoffersen, L., Podar, M., Chang, C., Hemscheidt, T., Trapido-Rosenthal, H.G., Short, J.M., Bidigare, R.R., and Mathur, E.J. (2006) High throughput cultivation for isolation of novel marine organisms. Oceanography 19:120-125.
Owen, R., Mitchelmore, C., Woodley, C., Trapido-Rosenthal, H., Galloway, T., Depledge, M., Readman, J., Buxton, L., Sarkis, S, Jones, R. and Knap, A. (2005) A common sense approach for confronting coral reef decline associated with human activities. Mar. Pol. Bull. 51:481-485.
Trapido-Rosenthal, H. G., Zielke, S., Owen, R.J., Buxton, L., Boeing, B., Bhagooli, R., and Archer, J.A. (2005) Increased zooxanthellae nitric oxide synthase activity is associated with coral bleaching. Biol. Bull. 208:3-6.

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